https://shareme.joinjet.org/ojs/index.php/shareme <p>SHAREme- Scientific Hub of Applied Research in Emerging Medical science &amp; technology is a leading international journal for publication of new ideas, the state of the applied research results and fundamental advances in all aspects of Medical Science and technology started in 2022. SHAREme is a scholarly open access, peer reviewed international journal with a primary objective to provide the academic community and industry for the submission of their original research.</p> en-US [email protected] (Editor in Chief) [email protected] (Jeya Prakash R) Sun, 01 Sep 2024 12:58:14 +0000 OJS 3.3.0.8 http://blogs.law.harvard.edu/tech/rss 60 https://shareme.joinjet.org/ojs/index.php/shareme/article/view/13 <p><span class="fontstyle0">P</span><span class="fontstyle0">rimary amoebic meningoencephalitis (PAM) is a rare but highly fatal infection of the central nervous system caused by the free-living amoeba, Naegleria fowleri. Known colloquially as the brain-eating amoeba, N. fowleri is predominantly found in warm freshwater environments, such as lakes, rivers, and poorly maintained swimming pools. Infection typically occurs when contaminated water enters the nasal passages, allowing the amoeba to travel to the brain via the olfactory nerve. Primary amoebic meningoencephalitis progresses rapidly, with symptoms ranging from headache and fever to seizures and coma, often resulting in death within a week of symptom onset. This review provides a comprehensive overview of N. fowleri, including its biology, epidemiology, pathogenesis, clinical presentation, diagnostic challenges, current treatment strategies, and public health measures for prevention. We also explore emerging research and future directions for developing more effective diagnostic and therapeutic approaches. Understanding the complex interaction between N. fowleri and its human host is crucial for improving outcomes and developing effective prevention strategies. This review aims to enhance awareness and understanding among healthcare providers and public health professionals to better manage and prevent this devastating infection.</span> </p> N Sriram , Aithamraju Satish Chandra Copyright (c) 2024 Scientific Hub of Applied Research in Emerging Medical science & technology https://shareme.joinjet.org/ojs/index.php/shareme/article/view/13 Mon, 02 Sep 2024 00:00:00 +0000 https://shareme.joinjet.org/ojs/index.php/shareme/article/view/21 <p>The Argus Safety Database is a comprehensive pharmacovigilance solution designed to manage drug safety data and ensure compliance with global regulatory requirements. In today’s complex pharmaceutical landscape, the management of adverse event (AE) data has become critical for drug safety surveillance. Argus Safety provides an all-encompassing platform that supports case processing, signal detection, medical coding, and automated regulatory reporting. This review article delves into the key features, architecture, and functionality of the Argus Safety Database, exploring its significant role in both pre-marketing and post-marketing drug safety. Additionally, the article evaluates the software's strengths, limitations, and its comparative advantage over other pharmacovigilance systems. Finally, it provides insights into future advancements, such as artificial intelligence (AI) integration and real-time analytics, which are likely to shape the next generation of drug safety systems. The review concludes with a detailed analysis of how Argus Safety contributes to improved patient outcomes, efficient regulatory compliance, and more proactive pharmacovigilance efforts.</p> Sriram Nagarajan, Shaktiprasad Pradhan Copyright (c) 2024 https://shareme.joinjet.org/ojs/index.php/shareme/article/view/21 Sat, 19 Oct 2024 00:00:00 +0000